This is the sequel of the spinoff of Nyotaika Suru Kusuri o Hirotte Kita series by AB10 about a school male club who use the same drug from the previous series to turn in to girls so they can have sex and do blowjobs
It seems blondie is giving up on his manhood or something and I guess glasses-guy is a new member to the club or something. I really love AB10's art style but I know it's not for everyone, which makes me sad that I'll probably never see his works in English.