You know, we can actual answer that question "Can Minotaur breed with humans" from a historical perspective in a kinda interesting way.
In the myth, King Minos told society that the Minotaur born to his wife was the result of an unholy union between her and a Bull. He didn't wish to condemn the child to death as being a just ruler was the entire image of his reign; thus he created the labyrinth to not allow the monstrosity free reign on his Kingdom, and the people hailed him as a just king for this. He even invited adventurers into the labyrinth to attempt to slay the Minotaur, promising fame and riches to the hero who managed.
The tragedy of the myth (as is usually the case with the Greeks) is that the premise of the "Minotaur" being born of man and bull was bullshit (lol). The child was merely the heinously deformed progeny of Minos himself; thus he built the Labyrinth to protect his reigns legitimacy. The "Heros" Minos "invited" to trudge through the Labyrinth were mostly just criminals otherwise sentenced to die. The Labyrinth was essentially doom to all beyond the "Minotaur" that dwelled there and the King, with his various secret passages, who often visited his son to see that he was healthy and alive.
King Minos even came to love his son deeply, as he (the son) had an incredibly gentle heart and a keen mind through the education of the books Minos allowed him. When Thesesus eventually conquered the Labyrinth and slayed the Minotaur, the citizens believed the Tears streaming down Mino's face during the celebration were tears of joy at finally being rid of such a terrible monster and reminder of his wife's infidelity.
If you follow the story from the perspective of common tongue (as history largely has), then you will draw the conclusion that a Minotaur, being half-human, may successfully breed with a human. If you subscribe to the tragic perspective; you then reject that the subjects here are even Minotaur at all. The fact that we never see what the Bull half of their body actually looks like gives credence to the ambiguity of what the "Minotaur" actually are. Ultimately, whether you believe in the myth of the Minotaur or not: These bitches be very pregnant.