https://www.dlsite.com/maniax/work/=/product_id/RJ01527619.html

[Synopsis]

TS pills!! A dream drug that switches your gender just by taking it!!
Shota's friend Hajime teases him about not having a girlfriend recently.
When he goes to Hajime's house after work and accepts his invitation, he finds a beautiful girl with huge breasts there, unfamiliar to him!
Hajime and Shota who has transformed into a woman after taking the TS drug.
Friday night, two tipsy people alone in a room... Naturally, that leads to──────
This is a lighthearted gender change story where the TS girl starts out having sex purely out of curiosity but gradually loses her composure as the story progresses into the middle and end.

Base +28, nuts987 +14, hidekohi +6

如果是无副作用那这💊会堪比飞叶子的成瘾性

Base +6