The comic takes place in her Mismatch world, which focuses on monster sexings and a cafe/sex shop that uses transformation potions (among other things) for kinky effect. The woman, Ririn, is a waitress at said shop, and this is her indulging one of her regulars. More information on the setting can be found on her twitter.
This is the first true comic by the artist, and true to form, she worked way too hard on it.